仕様

• 製品名：p16 Polyclonal Antibody
• 略名：p16
• 研究領域：Cancer, Cell biology
• 製品説明：This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53.
• 抗原：Synthesized peptide derived from the N-terminal region of human p16
• 免疫動物：Rabbit
• アイソタイプ：IgG
• 種交差性：Human,Mouse
• Clone №：
• Gene ID：1029
• Gene Accession：
• Protein Accession No：P42771
• アプリケーション：WB,ELISA
• 標識：Unconjugated
• 抗体種別：Polyclonal
• バッファー：PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
• 濃度：1mg/mL
• 容量：20μL
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