仕様

• 製品名：Frizzled-7 Polyclonal Antibody
• 略名：Frizzled-7
• 研究領域：Stem cells,Cancer,Epigenetics
• 製品説明：Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
• 抗原：Synthesized peptide derived from the N-terminal region of human Frizzled-7
• 免疫動物：Rabbit
• アイソタイプ：IgG
• 種交差性：Human,Mouse
• Clone №：
• Gene ID：8324
• Gene Accession：
• Protein Accession No：O75084
• アプリケーション：WB,IF,ELISA
• 標識：Unconjugated
• 抗体種別：Polyclonal
• バッファー：PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
• 濃度：1mg/mL
• 容量：20μL
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